Chief of Staff - Optexity
People & HR, Operations
San Francisco, CA, USA
About Optexity
Optexity is a product-driven research lab building clinical reasoning and computer use models on data no other lab can reach. We deploy directly inside clinics and hospitals — including systems with no APIs, using integration infrastructure we've built and open-sourced — and in return become their preferred partner. That gives us proprietary clinical reasoning trajectories from practicing physicians, and a feedback loop between real patient encounters, our models, and the products built on top of them.
We're a small, fast-moving founding team with multiple published papers in NeurIPS, ICML, CVPR etc and background from Apple, Amazon, Microsoft, CMU, IIT.
We are backed by world-class investors and leaders like Jeff Dean, Neotribe VC, PearVC, Together Fund and Zapier Fund.
How we work
Customer obsession — we start with the customer and work backwards
Intellectual honesty — ideas matter more than titles; we communicate directly and assume good intent, even in disagreement
Bias for action — we build and learn with customers rather than debate in the abstract
Extreme ownership — we own outcomes, not just tasks, and see problems through
About the role
This is not an EA role, and not a strategy role — it's a hands-on generalist operator who owns the business, legal, and people infrastructure that lets a small team move fast without breaking. You'll be the person who makes sure the company runs: contracts get signed, people get paid, compliance holds up, and nothing critical falls through the cracks. You'll work directly with the founders and build the operational backbone from close to zero.
Why this role exists
Legal, HR, accounting, payroll, compliance, and day-to-day operations all sit on the founders' plates today, alongside product and engineering. In a healthcare company, this surface area is heavier than usual — BAAs, HIPAA and state privacy obligations, and customer contracts can't be an afterthought. We need one person to own all of it end to end: not just execute tasks, but build the systems, vendor relationships, and processes so these functions run reliably as we scale.
What you'll do
Legal & contracts — manage outside counsel, own the contract lifecycle (customer agreements, BAAs, NDAs, vendor and consulting agreements), and keep corporate housekeeping in order: cap table administration, board and investor documents, entity and state registrations
Compliance — own the operational side of HIPAA and state privacy compliance, coordinate audits and security certifications (e.g. SOC 2) as they come up, and maintain the policies, records, and vendor due-diligence that customers and regulators expect
HR & people ops — run onboarding/offboarding, offer letters, benefits and PEO administration, immigration/visa support for the team, and keep employee policies and records clean and current
Accounting & payroll — own bookkeeping oversight with our accountants, run payroll and contractor payments, manage AP/AR, expenses, banking, and the monthly close
Everyday operations — manage vendors, software and tooling, insurance, and the logistics of a fast-growing team; be the default owner for the operational thing no one else is holding
Founder leverage — take ambiguous operational problems off the founders' plates, structure them, and drive them to done
What we look for
A generalist who's comfortable owning many unrelated functions at once and context-switching cleanly between them
Strong execution and follow-through — you close loops and things don't slip
Highly organized and detail-oriented, with good judgment about what's genuinely important vs. merely urgent
Operates in ambiguity and builds process where none exists, without waiting for perfect instructions
Trustworthy with sensitive legal, financial, and personnel information
Willing to do unglamorous, high-value work
Fast learner with genuine interest in the operational and regulatory side of a healthcare company
Nice to have
Prior chief-of-staff, business ops, or startup operations experience
Exposure to legal, HR, finance, or compliance functions
Familiarity with healthcare compliance (HIPAA, BAAs) or other regulated environments
Experience standing up processes and vendors at an early-stage company
What you get
Direct, daily work with the founders, plus exposure to board and investor conversations
True zero-to-one scope — building the operational foundation of the company, not executing a fixed playbook
Competitive salary and meaningful equity